Sentences to life in jail were upheld against Farhan Mutlaq Saleh, the former deputy director of operations for the armed forces, and Sabir al-Douri, former director of military intelligence, Munir Hadad, the appellate court judge, said.
Ousted regime
Saddam himself was among the defendants when the trial began last August 21.
He was hanged four months later for his role in the deaths of more than 140 Shia Muslims in the town of Dujail in the first trial against major figures from the ousted regime.
Besides Saddam, three other figures from the former regime have been executed - all in the Dujail case.
They include Barzan Ibrahim, Saddam's half-brother and former intelligence chief, and Awad Hamed al-Bandar, who headed the Revolutionary Court that sentenced the Dujail victims to death.
Both were hanged in January.